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Fabrication and characterization of andrographolide analogue (3A.1) nanosuspensions stabilized by amphiphilic chitosan derivatives for colorectal cancer therapy
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Elsevier, 2019)Recently, 19-tert-butyldiphenylsilyl-8,17-epoxy andrographolide (3A.1) is an andrographolide analogue which was a promising chemotherapeutic agent against some types of cancer. However, this compound has an extremely low ... -
PEGylated Plier-Like Cationic Niosomes on Gene Delivery in HeLa Cells
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Trans Tech Publications Ltd, 2019)Lipid-based formulations have been used as a widespread carrier to improve gene delivery. Niosomes, one type of lipid-based vesicular systems are produced from non-ionic surfactants which are generally inexpensive and ... -
Dual-Charge Nanofiber Mats Made of Chitosan(CS)/Poly(Vinyl Alcohol) (PVA) and Poly-(Acrylic Acid-Co-Maleic Acid) (PAMA)/PVA
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Trans Tech Publications Ltd, 2019)Nanofibers have been widely used for tissue engineering. Using charged polymers for the preparation of nanofibers can be useful for the loading of substances or macromolecules. Dual charge nanofiber mats are expected to ... -
Optimization of Boesenbergia rotunda Extract-Loaded Polyvinyl Alcohol Hydrogel Wound Dressing by Box-Behnken Design
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Trans Tech Publications Ltd, 2019)The objective of this study was to optimize fabrication variables that affected desirable properties of dressings. Boesenbergia rotunda extract incorporated PVA hydrogels for wound dressings were fabricated by freeze-thaw ... -
Folate-Functionalized Amphiphilic Chitosan Polymeric Micelles Containing Andrographolide Analogue (3A.1) for Colorectal Cancer
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Trans Tech Publications Ltd, 2019)A site-specific drug delivery system of anticancer agents has been delveloped to enhance the therapeutic efficacy and reduce toxicity to the normal tissue. Semi-synthetic andrographolide analogue 3A.1 (19-tert-butyldiphe ...