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Controlled release of felodipine from 3D-printed tablets with constant surface area: Influence of surface geometry
In this study, 3D-printed tablets with a constant surface area were designed and fabricated using polylactic acid (PLA) in the outer compartment and polyvinyl alcohol and felodipine (FDP) in the inner compartment. The ...
Optimized Taste-Masked Microparticles for Orally Disintegrating Tablets as a Promising Dosage Form for Alzheimer’s Disease Patients
The objective of this research was to optimize the tasted-masked microparticles for orally disintegrating tablets containing donepezil hydrochloride using quality risk assessment and design of experiment approaches. The ...
Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by simulated wetting test and in vitrodisintegration test
The disintegration time is critical for characterizing orally disintegrating tablets (ODTs), according to regulatory standards. The current study aimed to assess the effect of superdisintegrants such as sodium starch ...
Salt formation, stability study and tablet formulation of mefenamic acid with improved drug dissolution
Mefenamic acid is characterized by a low oral bioavailability due to its slow dissolution and absorption. The purpose of this study was to investigate the effect of salt formation on dissolution of mefenamic acid and its ...
Development and optimization of Clinacanthus nutans liquid spray using a two-level full factorial design
This study aimed to develop and optimize a topical Clinacanthus nutans liquid spray that dries quickly after spraying and has low stickiness. An experimental design was adopted to evaluate the effects of the amounts of ...
Use of risk assessment and Plackett-Burman design for developing resveratrol spray-dried emulsions: A quality-by-design approach
In this study, the resveratrol spray-dried emulsions were developed using a quality-by-design approach. Further, the product and process factors that affected the quality of the spray-dried emulsions were analyzed and ...
Physical stability of different chitosan salts in matrix tablet formulations
This study aimed to evaluate the physical stability of chitosan (CS) and its salt forms, including chitosan glycolate (CGY) and chitosan lactate (CL), as diluent in matrix tablets for the modified-release dosage form. ...
Applying information and computer technologies in various industrial sectors
In 2021, Science, Engineering and Health Studies (SEHS) has collaborated with the Asia Joint Conference on Computing (AJCC) to provide a platform for the authors to publish their research works on information and computer ...
Impact of drug loading method on drug release from 3D-printed tablets made from filaments fabricated by hot-melt extrusion and impregnation processes
The purpose of this study was to investigate the impact of the drug loading method on drug release from 3D-printed tablets. Filaments comprising a poorly water-soluble model drug, indomethacin (IND), and a polymer, polyvinyl ...
Fabrication of indomethacin-loaded polyvinyl alcohol filaments through hot-melt extrusion
The main objective of this study was to prepare the drug-loaded filament by hot-melt extrusion technique. Indomethacin (IND) was used as a model drug and polyvinyl alcohol (PVA) was used to produce the filament. The IND-PVA ...