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Prevalence of causative bacteria and clinical outcomes among patients with meningitis at a regional central hospital in Thailand
This study aimed to identify causative bacteria and to investigate the outcomes of treatment and the appropriate empirical regimen among patients with bacterial meningitis. Patients with bacterial meningitis admitted at ...
Clinical outcomes by treatment type and factors associated with mortality among patients with candidemia at a Thai university hospital
Candidemia is a major cause of morbidity and mortality among hospitalized patients in Thailand. In this study we aimed to retrospectively investigate the clinical outcomes by treatment regimen and the factors associated ...
Clinical factor related to international normalized ratio changes in warfarin users who underwent heart valve replacement at warfarin clinic of Phramongkutklao Hospital
Warfarin is oral anticoagulant that has been used for prevention of systemic thromboembolism in valve replacement patients. There are many factors that can change the international normalized ratio (INR) in warfarin users. ...
Clinical outcomes and mortality risk factors among intensive care unit patients with bacteremia at a university hospital
This study aimed to determine the prevalence and antimicrobial susceptibility of causative pathogens associated with 30-day mortality among intensive care unit (ICU) patients with bloodstream infections as well as to analyze ...
Clinical outcomes and mortality rate among critically ill patients with sepsis or septic shock treated with meropenem
Sepsis and septic shock are associated with high mortality. Meropenem is currently used as empirical therapy in patients with sepsis and septic shock. The objectives of this study were 1) to study the causative pathogen ...
Colistin plus sulbactam or fosfomycin against carbapenem-resistant acinetobacter baumannii: improved efficacy or decreased risk of nephrotoxicity?
Background
Acinetobacter baumannii has been recognized as a cause of nosocomial infection. To date, polymyxins, the last-resort therapeutic agents for carbapenem-resistant A. baumannii (CRAB). Thus, the small number of ...
The Synergistic activity and optimizing doses of tigecycline in combination with aminoglycosides against clinical carbapenem-resistant klebsiella pneumoniae isolates
Carbapenem-resistant Enterobacteriaceae (CRE), especially carbapenem-resistant Klebsiella pneumoniae (CRKP), are among the largest pathogenic threats to humans. The available antibiotic treatment options for combating CRKP ...
The Potential use of ceftazidime-avibactam against carbapenem resistant klebsiella pneumoniae clinical isolates harboring different carbapenemase types in a Thai University Hospital
Purpose: MBL and OXA-48 genes in carbapenem-resistant Enterobacterales (CRE) have emerged as a major public health problem worldwide, including Thailand. Due to the lack of susceptibility data and dosing regimens of ...
Impact of pharmacist-led implementation of a community hospital-based outpatient parenteral antimicrobial therapy on clinical outcomes in Thailand
Few studies have analyzed community hospital-based parenteral anti-infective therapy (CohPAT). We aimed to assess the clinical impact of a pharmacist-led implementation of a clinical practice guideline (CPG) for CohPAT, ...
The First report of a methicillin-resistant staphylococcus aureus isolate harboring type IV SCCmec in Thailand
Methicillin-resistant Staphylococcus aureus (MRSA) is mostly found in Thailand in the hospital as a nosocomial pathogen. This study aimed to report the genetic characterization of a clinical community-acquired MRSA (CA-MRSA) ...