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Facile and green fabrication of biocatalytic chitosan beads by one-step genipin-mediated β-glucosidase immobilization for production of bioactive genistein
While glutaraldehyde is a commonly used cross-linker for enzyme immobilization, it is unsafe and requires the multi-step cross-linking procedure. Here, we report a facile, fast and cost-effective fabrication of immobilized ...
Fabrication and evaluation of chlorhexidine gluconate-incorporated chitosan-poly (vinyl alcohol) hydrogel films for infected wounds
Antibacterial dressings play an essential role in wound repair and infection control. This study aimed to fabricate chlorhexidine gluconate (CHX)-loaded chitosan-based hydrogel films via a physical cross-linking approach. ...
Development of mucoadhesive chitosan-Iodoacetamide buccal tablets for local delivery of dextromethorphan
This study aimed to synthesize a chitosan (CHI) derivative, chitosan-iodoacetamide (CHI-IA), with enhanced mucoadhesive properties and develop buccal mucoadhesive tablets of CHI-IA for local delivery of dextromethorphan ...
Physical stability of different chitosan salts in matrix tablet formulations
This study aimed to evaluate the physical stability of chitosan (CS) and its salt forms, including chitosan glycolate (CGY) and chitosan lactate (CL), as diluent in matrix tablets for the modified-release dosage form. ...