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Doxorubicin-loaded N-naphthyl-N,O-succinyl chitosan micelles for colon cancer treatment
Doxorubicin (Dox) is one of the effective treatments in many types of cancer, such as breast cancer and ovarian cancer. However, the clinical settings of this drug are limited by its low therapeutic efficiency and high ...
Design and Optimization of 3D-Printed Gastroretentive Floating Devices by Central Composite Design
This study aimed to optimize the size of capsule-shaped 3D-printed devices (CPD) using an experimental design by the response surface methodology to provide a gastroretentive drug delivery system (GRDDS) with optimal ...
Fabrication of a Floating Device of Domperidone Tablets Using 3D-Printing Technologies
Gastro-retentive drug delivery systems (GRDDS) have been developed with the aim of prolonging drug release. In this study, floating device systems (FDS) were developed and incorporated with a domperidone tablet (Motilium-M®). ...
Preparation and evaluation of 6-Maleimidohexanoic acid grafted chitosan nanoparticles as a novel carrier for intranasal protein delivery
In this study, 6-maleimidohexanoic acid grafted chitosan nanoparticles (MHA-CS NPs) were prepared and evaluated the efficiency of intranasal protein delivery as compared with well-known chitosan nanoparticles (CS NPs). ...