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Development and evaluation of p-chlorophenyl benzyl ether-loaded microemulsions for transdermal delivery
p-Chlorophenyl benzyl ether (CBE) has been reported to be a new skin brightening agent. Because of its strong inhibitory effect on tyrosinase and its high safety, CBE was selected as a model antityrosinase compound in ...
Fabrication, characterization and comparison of α-arbutin loaded dissolving and hydrogel forming microneedles
In this study, polyacrylic acid-co-maleic acid (PAMA) and polyvinyl alcohol (PVA) (1:4) were used to fabricate dissolving microneedles (DMNs) and hydrogel forming microneedles (HMNs) which incorporated α-arbutin. Αlpha-arbutin ...
Chitosan capped-gold nanoparticles as skin penetration enhancer for small molecules: A study in porcine skin
Skin is considered one of the most convenient sites for drug administration. The present study evaluated the effect of gold nanoparticles stabilized by chitosan (CS-AuNPs) and citrate ions (Ci-AuNPs) on skin permeation of ...