Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรม
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SYNTHESIS AND EVALUATION OF MUCOADHESIVE NANOPARTICLES FOR ANTICANCER DRUG DELIVERY
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)The purpose of this study was to synthesize and characterize new mucoadhesive polymers and fabricate mucoadhesive polymeric nanoparticles (NPs) for anticancer drug delivery. 6-maleimidohexanoic acid (MHA)-conjugated chitosan ... -
Development of protein extracts -loaded nanocarriers combination with microspicules for transdermal delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)Proteins extracted from natural products are hydrophilic macromolecules which limited the ability to passively penetrate through the skin. The combination of penetration enhancing techniques such as nanocarriers and sponge ... -
Development of targeted polymeric nanoparticles for chemotherapeutics delivery to head and neck squamous cell carcinoma
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 26/11/2021)The purpose of this study was to develop polymeric nanoparticles (NPs) loaded with chemotherapeutic agents using different NPs preparation methods to target head and neck squamous carcinoma cells (HNSCC) by passive targeting ... -
Application of microneedles and electroporation for antigen delivery to enhance the efficiency of skin vaccination
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 17/8/2018)In this study, the effect of different transdermal drug delivery methods, including solid microneedles (MNs) patch (poke and patch approach), electroporations (EPs) patch, solid MNs+EPs patch, and hollow MN (poke and flow ... -
Mechanistic phase inversion of saturated fatty acid-based in situ forming matrix for pharmaceutical applications
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)Saturated fatty acids of different chain lengths (C8–C18) were studied as matrix forming agents in this investigation as the localised injectable vancomycin HCl (VCM)-loaded solvent exchange-induced in situ forming matrices ...