Browsing Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรม by Issue Date
Now showing items 1-20 of 44
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SYNTHESIS AND EVALUATION OF MUCOADHESIVE NANOPARTICLES FOR ANTICANCER DRUG DELIVERY
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)The purpose of this study was to synthesize and characterize new mucoadhesive polymers and fabricate mucoadhesive polymeric nanoparticles (NPs) for anticancer drug delivery. 6-maleimidohexanoic acid (MHA)-conjugated chitosan ... -
Development of protein extracts -loaded nanocarriers combination with microspicules for transdermal delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)Proteins extracted from natural products are hydrophilic macromolecules which limited the ability to passively penetrate through the skin. The combination of penetration enhancing techniques such as nanocarriers and sponge ... -
Development and mechanistic transformation of antimicrobial agent-loaded in-situ forming gel and microparticle using Eudragit RS and rosin as matrix formers for periodontal pocket delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)This research aimed to prepare and evaluate in situ forming gel (ISG) and in situ forming microparticle (ISM) containing antibiotics for periodontitis treatment employing Eudragit RS (ERS) and rosin (R) as the matrix forming ... -
Development and optimization of finasteride-loaded microemulsions for transdermal delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 12/7/2019)This study aimed to examine the effect of finasteride (FN) to dermal papilla cells (DPCs) and human primary dermal papilla cells (HDPCs) then FN–loaded microemulsions (MEs) for transdermal delivery were developed and ... -
Fabrication and evaluation of shellac/polyvinylpyrrolidone nanofibers loaded with monolaurin as wound dressing mats using factorial designs
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 12/7/2019)Due to their ultrafine network structures, electrospun nanofibers have been potentially used for wound dressing application as they could provide a rapid wound epithelialization, an enhanced oxygen and nutrients delivery ... -
Interaction of pharmaceutical excipients and chitosan derivatives with organic cation transporters and potential for the prevention of cisplatin-induced nephrotoxicity
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 12/7/2019)Pharmaceutical excipients are pharmacologically inert, however, they have been reported to have several biological effects. They showed an effects on several transport function of uptake and efflux drug transporters, these ... -
Application of microneedles and electroporation for antigen delivery to enhance the efficiency of skin vaccination
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 17/8/2018)In this study, the effect of different transdermal drug delivery methods, including solid microneedles (MNs) patch (poke and patch approach), electroporations (EPs) patch, solid MNs+EPs patch, and hollow MN (poke and flow ... -
Mechanistic phase inversion of saturated fatty acid-based in situ forming matrix for pharmaceutical applications
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)Saturated fatty acids of different chain lengths (C8–C18) were studied as matrix forming agents in this investigation as the localised injectable vancomycin HCl (VCM)-loaded solvent exchange-induced in situ forming matrices ... -
Development of andrographolide analogue (3A.1)-loaded nanocarriers and 3A.1 nanosuspensions for cancer therapy
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)In this study, 19-tert-butylsilyldiphenyl-8,17-epoxy andrographolide (3A.1)-loaded nanocarriers and 3A.1 nanosuspensions were developed for improving its aqueous solubility and antitumor efficacy. First, the pH-sensitive ... -
Development of alpha-arbutin and resveratrol-loaded dissolving microneedles for skin depigmentation
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)In this study, polymeric dissolving microneedles (DMNs) were developed to enhance the transdermal delivery of skin depigmentation agents into the melanocytes where melanin is synthesized. Alpha-arbutin (AA) is a well-known ... -
DEVELOPMENT OF PLIER-LIKE CATIONIC NIOSOMES FOR GENE DELIVERY AGAINST BREAST CANCER CELLS
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)In this study, novelly synthesized plier-like cationic lipids (PCLs, i.e., PCL-A, -B and -C) were used to formulate plier-like cationic niosomes (PCNs) for nucleic acid delivery. The molar ratio of PCL-A was primarily ... -
Mucoadhesive properties of pectins and their mechanisms
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2006) -
Effect of chitosan salts on in vitro transfection efficiency for gene delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2007) -
การเตรียมและการใช้ประโยชน์ของแป้งมันมือเสือดัดแปรด้วยหมู่คาร์บอกซีเมธิล
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2008) -
Development of multiple emulsions for drug stability enhancement
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2009) -
Development of lipid nanoparticles for drug delivery systems
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2009) -
Absorption enhancement of Itraconazole in gastrointestinal tract using Nanotechnology
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2010) -
Enhancement of paracellular permeability across Caco-2 Cells by modified Chitosan derivatives
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2010) -
Development of chitosan nano/microparticles for colonic drug delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2010) -
Development of shellac esters as alternative enteric polymers through solid-state reactions
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2011)