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A triterpenoid friedelan-3ß-ol isolated from Euphorbia lactea exhibited cytotoxic activity against HN22 cells by inducing an S-phase cell cycle arrest
The anticancer activity of Euphorbia lactea Haw. (E. lactea) has been observed by our lab and other research groups; however, the identity of the bioactive compounds harboring the anticancer effect remains unknown. Here, ...
Effect of Semi-synthetic Andrographolide Analogue-loaded Polymeric Micelles on HN22 Cell Migration
Semi-synthetic andrographolide (AG) analogue, namely 19-tert-butyldiphenylsilyl-8,17-epoxy andrographolide, or 3A.1, is an anticancer drug. However, the major problem of 3A.1 is poor water solubility hindering its clinical ...
Synergistic activity of friedelan-3β-ol isolated from Euphorbia lactea and doxorubicin against MDA-MB-231 breast cancer cell line
The cytotoxic activity of three triterpenoid compounds namely, friedelin [1], friedelan-3β-ol [2] and taraxerol [3] isolated from hexane fraction Euphorbia lactea Haw. was investigated in breast cancer cell lines MDA-MB-231 ...