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Melatonin receptor as a drug target for neuroprotection
Background: Melatonin, a neurohormone secreted from the pineal gland, circulates throughout the body and then mediates several physiological functions. The pharmacological effects of melatonin can be mediated through its ...
Synergistic effect of doxorubicin and siRNA-mediated silencing of Mcl-1 using cationic niosomes against 3D MCF-7 spheroids
Chemotherapy is a vital option for cancer treatment; however, its therapeutic outcomes are limited by dose-dependent toxicity and the occurrence of chemoresistance. siRNAs have emerged as an attractive therapeutic option ...