β-cyclodextrin (β-CD) is interesting for using as a matrix former of the solvent exchange-induced in situ forming drug delivery system because of its apparent high solubility in some injectable solvents including 2-pyrrolidone ...

The objectives of this research were to develop the microbeads containing thiolatedpectin–doxorubicin (DOX) conjugates for colorectal cancer treatment. Thiolated pectin–DOXconjugates with reducible disulfide bond were ...

Resveratrol (RVT) possesses various potential advantages to human health. However, RVT has some disadvantages i.e. poor water solubility and photo-sensitivity. The aims of this research were to improve the dissolution ...

Natural resins such as aloe, benzoin, propolis, rosin and gamboge consist of aqueous insoluble components; therefore, they are possibly applied as matrix forming agents of drug-loaded localized solvent exchange-induced in ...

Rhein, a key component of anthraquinones, is a crucial active compound in Senna alata leaves with a variety of pharmacological effects. Achieving high-quality herbal extracts necessitates selecting suitable extraction ...

The in-situ forming matrix (ISM) established through solvent removal phase-inversion, emerges as a promising method for treating periodontitis by administering it to the periodontal pocket. This innovative drug delivery ...

The stem and rhizome waste of pineapple plant (Ananas comosus L. Merr.) is normally disposed of via a burning process, which can cause environmental pollution. In order to improve the limited properties of native pineapple ...

Bigels or biphasic gels are semisolid formulations offering the combined advantages of both hydrogels and oleogels. They are gaining interest in food, cosmetic and pharmaceutical applications. The aim of this study was to ...