Browsing Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรม by Issue Date
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Synthesis of octenyl succinate pineapple starch and evaluation for its application as nanoemulsion stabilizer
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 12/7/2019)The stem and rhizome waste of pineapple plant (Ananas comosus L. Merr.) is normally disposed of via a burning process, which can cause environmental pollution. In order to improve the limited properties of native pineapple ... -
Novel biphasic gels containing mixture of silicone oil and sesame oil for topical drug delivery
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 12/7/2019)Bigels or biphasic gels are semisolid formulations offering the combined advantages of both hydrogels and oleogels. They are gaining interest in food, cosmetic and pharmaceutical applications. The aim of this study was to ... -
FLUID PROPERTIES, SOLVENT EXCHANGE AND TRANSFORMATION OF IN SITU FORMING GEL AND MICROPARTICLES USING BETA-CYCLODEXTRIN AS A MATRIX FORMER
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 2/1/2019)β-cyclodextrin (β-CD) is interesting for using as a matrix former of the solvent exchange-induced in situ forming drug delivery system because of its apparent high solubility in some injectable solvents including 2-pyrrolidone ... -
Development and characterization of resveratrol dry emulsions using Quality-by-Design approach
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 2/1/2019)Resveratrol (RVT) possesses various potential advantages to human health. However, RVT has some disadvantages i.e. poor water solubility and photo-sensitivity. The aims of this research were to improve the dissolution ... -
pH-responsive dextrin nanogels for colorectal cancer drug delivery
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2014) -
Pectin-Doxorubicin Conjugates for treatment of colorectal cancer
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(มหาวิทยาลัยศิลปากร, 2016)The objectives of this research were to develop the microbeads containing thiolatedpectin–doxorubicin (DOX) conjugates for colorectal cancer treatment. Thiolated pectin–DOXconjugates with reducible disulfide bond were ... -
Injectable antimicrobial agent-loaded in situ forming eudragit L, nitrocellulose and zein-based solvent removal phase-inversion matrices for periodontitis treatment
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 24/11/2023)The in-situ forming matrix (ISM) established through solvent removal phase-inversion, emerges as a promising method for treating periodontitis by administering it to the periodontal pocket. This innovative drug delivery ... -
Mechanistic phase transition and computerized modeling of solvent exchange-based in situ forming matrix systems for treatment of oral cavity infectious diseases
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 24/11/2023)In situ matrix-forming systems possess a unique capability for spontaneous transformation into a solid matrix upon administration to the target site. This approach offers less invasive and prolonged drug release at the ... -
Natural resins-based in situ forming gel for localized antimicrobial and anticancer delivery systems
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 25/11/2022)Natural resins such as aloe, benzoin, propolis, rosin and gamboge consist of aqueous insoluble components; therefore, they are possibly applied as matrix forming agents of drug-loaded localized solvent exchange-induced in ... -
Optimization and evaluation of rhein-rich Senna alata leaf extract incorporated shellac electrospun nanofibers using design of experiments
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 28/6/2024)Rhein, a key component of anthraquinones, is a crucial active compound in Senna alata leaves with a variety of pharmacological effects. Achieving high-quality herbal extracts necessitates selecting suitable extraction ... -
Molecular/micro-macroscopic characteristics of effervescent eutectic ibuprofen-poloxamer matrices fabricated with melt granulation
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 28/6/2024)Employing a combination of conventional and advanced techniques, the multiscale characterization of effervescent matrix tablets containing the ibuprofen (IBU)-poloxamer 407 (P407) eutectic mixture yielded valuable insights ... -
DESIGNING FIXED DOSE COMBINATION OF GLIPIZIDE AND FELODIPINE USING FUSED DEPOSITION MODELING 3D PRINTING
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 3/7/2026)Poor medication adherence in chronic diseases such as hypertension and diabetes affects approximately 50% of patients, primarily due to complex dosing regimens. This research investigated fused deposition modeling (FDM) ...