RSS 1.0Organic Chemistry
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Synthesis and bioactivity evaluation of 2-substituted indoles
Collection: Theses (Ph.D) - Organic Chemistry / ดุษฎีนิพนธ์ - เคมีอินทรีย์Type: Thesis(Silpakorn University, 10/7/2020)Indoles are heterocylic compounds. It containing pyrrole ring and benzene ring fused to α,β position. Indoles are common substructure in many alkaloids, a biologically accepted pharmacophore, for example, anticancer, ... -
Design and syntheses of visible and near-infrared fluorescent sensors for copper and fluoride ion detection
Collection: Theses (Ph.D) - Organic Chemistry / ดุษฎีนิพนธ์ - เคมีอินทรีย์Type: Thesis(Silpakorn University, 12/7/2019)Two novel fluorescence sensors were developed for detection of copper and fluoride ions. Sensors I composed of an aza-boron-dipyrromethene (aza-BODIPY) core as near-infrared (NIR) fluorophore covalently bound to two ... -
Synthesis and Biological Activities Evaluation of Isomeric Iheyamine Derivatives
Collection: Theses (Master's degree) - Organic Chemistry / วิทยานิพนธ์ - เคมีอินทรีย์Type: Thesis(Silpakorn University, 2/1/2019)Iheyamine A and B are annulated bis-indole alkaloid natural products which were isolated from an ascidian, Polycitorella sp.. Both compounds exhibited moderately anticancer activity against murine leukemia P388 cells, human ... -
Synthesis and Biological Activities of Methyl 5-(hydroxymethyl)-2-furan carboxylate and Derivatives
Collection: Theses (Master's degree) - Organic Chemistry / วิทยานิพนธ์ - เคมีอินทรีย์Type: Thesis(Silpakorn University, 2/1/2019)Methyl 5- (hydroxymethyl) -2-furan carboxylate is a furan natural products. It was reported to be isolated from Streptomyces sp., found in rhizomes of Zingiber zerumbet in Chanthaburi province. This compound showed significant ... -
SYNTHETIC STUDIES AND BIOLOGICAL ACTIVITY OF SPIROINDOLIZIDINE-OXINDOLE AND INDOLIZIDINE ALKALOIDS DERIVATIVE
Collection: Theses (Ph.D) - Organic Chemistry / ดุษฎีนิพนธ์ - เคมีอินทรีย์Type: Thesis(Silpakorn University, 25/11/2022)Spiroindolizidine-oxindole and indoloquinolizidine belong to an important class of alkaloids with variety of structures and biological activites. For example, rhynchophylline and mitraphylline, natural product isolated ...