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Donepezil—an updated review of challenges in dosage form design
Donepezil hydrochloride (DPH) was first launched in 1997 as a choline esterase inhibitor (ChEI). The USFDA has approved it for treatment of Alzheimer's disease since it effectively enhances cholinergic activity by slowing ...
Optimized Taste-Masked Microparticles for Orally Disintegrating Tablets as a Promising Dosage Form for Alzheimer’s Disease Patients
The objective of this research was to optimize the tasted-masked microparticles for orally disintegrating tablets containing donepezil hydrochloride using quality risk assessment and design of experiment approaches. The ...