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Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by simulated wetting test and in vitrodisintegration test
The disintegration time is critical for characterizing orally disintegrating tablets (ODTs), according to regulatory standards. The current study aimed to assess the effect of superdisintegrants such as sodium starch ...
Salt formation, stability study and tablet formulation of mefenamic acid with improved drug dissolution
Mefenamic acid is characterized by a low oral bioavailability due to its slow dissolution and absorption. The purpose of this study was to investigate the effect of salt formation on dissolution of mefenamic acid and its ...
Development and optimization of Clinacanthus nutans liquid spray using a two-level full factorial design
This study aimed to develop and optimize a topical Clinacanthus nutans liquid spray that dries quickly after spraying and has low stickiness. An experimental design was adopted to evaluate the effects of the amounts of ...