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Donepezil—an updated review of challenges in dosage form design
Donepezil hydrochloride (DPH) was first launched in 1997 as a choline esterase inhibitor (ChEI). The USFDA has approved it for treatment of Alzheimer's disease since it effectively enhances cholinergic activity by slowing ...
Optimized Taste-Masked Microparticles for Orally Disintegrating Tablets as a Promising Dosage Form for Alzheimer’s Disease Patients
The objective of this research was to optimize the tasted-masked microparticles for orally disintegrating tablets containing donepezil hydrochloride using quality risk assessment and design of experiment approaches. The ...
Applying information and computer technologies in various industrial sectors
In 2021, Science, Engineering and Health Studies (SEHS) has collaborated with the Asia Joint Conference on Computing (AJCC) to provide a platform for the authors to publish their research works on information and computer ...
Impact of drug loading method on drug release from 3D-printed tablets made from filaments fabricated by hot-melt extrusion and impregnation processes
The purpose of this study was to investigate the impact of the drug loading method on drug release from 3D-printed tablets. Filaments comprising a poorly water-soluble model drug, indomethacin (IND), and a polymer, polyvinyl ...