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Optimal tigecycline dosage regimens in patients infected with carbapenem-resistant Enterobacteriaceae
We aimed to evaluate the minimum inhibitory concentration (MIC) values of tigecycline for carbapenem-resistant Enterobacteriaceae (CRE) and to identify a potential regimen for achieving target values of the area under the ...
The prevalence of colistin-resistant Gram-negative bacteria isolated from hospitalized patients with bacteremia
This study sought to investigate the prevalence of colistin-resistant Gram-negative bacteria (CoR-GNB) among Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae isolated from patients ...
A comparison between conventional and stratified antibiograms for antibiotic empirical therapy among the most bacterial pathogens
Antibiogramsprovideimportant data regarding antimicrobial selection duringempirical therapy and formonitoringyearly trends in antimicrobial resistance in healthcare settings. Antibiograms tailored to hospital location ...
Is Early Monitoring Better? Impact of Early Vancomycin Exposure on Treatment Outcomes and Nephrotoxicity in Patients with Methicillin-Resistant Staphylococcus aureus Infections
Optimal early vancomycin target exposure remains controversial. To clarify the therapeutic exposure range, we investigated the association between vancomycin exposure and treatment outcomes or nephrotoxicity in patients ...
Vancomycin area under the curve and pharmacokinetic parameters during the first 24 Hours of treatment in critically ill patients using bayesian forecasting
Background
Currently, the achievement of the target area under the curve (AUC)/minimum inhibitory concentration ratio during the first 24 - 48 h of treatment is associated with reduced 30-day mortality and greater ...
Mono sulfamethoxazole/trimethoprim and Vancomycin combination antimicrobial zctivity against methicillin-resistant Staphylococcus aureus
Activity of trimethoprim/sulfamethoxazole (SXT) alone or in combination with vancomycin (VAN) was evaluated against methicillin-resistant Staphylococcus aureus (MRSA) from 26 clinical isolates from patients admitted to Hua ...
Optimizing the dosing regimens of tigecycline against vancomycin- resistant enterococci in the treatment of intra-abdominal and skin and soft tissue infections
Tigecycline was previously considered to have activity against vancomycin-resistant Enterococcus (VRE) isolates, but the optimal dose was not clarified. Thus, this study assessed the in vitro activity of tigecycline against ...
Antimicrobials as single and combination therapy for colistin-resistant pseudomonas aeruginosa at a university hospital in Thailand
Global infections with colistin-resistant Pseudomonas aeruginosa (CoR-PA) are increasing; there are currently very few studies focused on the antimicrobial susceptibility of CoR-PA isolates, and none from Thailand. Here, ...