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Treatment outcomes and their predictive factors in patients withEnterobacter spp., Serratia spp.,Citrobacter spp., Providencia spp., I-indole-positive Proteus spp., andMorganella spp, bloodstream infection
The present study examined the treatment outcomes and factors related to mortality in patients with Enterobacter spp., Serratia spp., Citrobacter spp., Providencia spp., I-indole-positive Proteus spp., and Morganella spp. ...
Optimal tigecycline dosage regimens in patients infected with carbapenem-resistant Enterobacteriaceae
We aimed to evaluate the minimum inhibitory concentration (MIC) values of tigecycline for carbapenem-resistant Enterobacteriaceae (CRE) and to identify a potential regimen for achieving target values of the area under the ...
The prevalence of colistin-resistant Gram-negative bacteria isolated from hospitalized patients with bacteremia
This study sought to investigate the prevalence of colistin-resistant Gram-negative bacteria (CoR-GNB) among Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae isolated from patients ...
A comparison between conventional and stratified antibiograms for antibiotic empirical therapy among the most bacterial pathogens
Antibiogramsprovideimportant data regarding antimicrobial selection duringempirical therapy and formonitoringyearly trends in antimicrobial resistance in healthcare settings. Antibiograms tailored to hospital location ...
Is Early Monitoring Better? Impact of Early Vancomycin Exposure on Treatment Outcomes and Nephrotoxicity in Patients with Methicillin-Resistant Staphylococcus aureus Infections
Optimal early vancomycin target exposure remains controversial. To clarify the therapeutic exposure range, we investigated the association between vancomycin exposure and treatment outcomes or nephrotoxicity in patients ...
The susceptibility of penicillin, ceftriaxone, and cefotaxime against Streptococcus pneumoniae isolated from patients with invasive pneumococcal diseases at a teaching hospital in Thailand
Objective: Pneumococcal disease is a severe invasive infection causing morbidity and death, so the appropriate antimicrobials are greatly important. We aimed to determine the minimum inhibitory concentration (MIC) of ...
Vancomycin area under the curve and pharmacokinetic parameters during the first 24 Hours of treatment in critically ill patients using bayesian forecasting
Background
Currently, the achievement of the target area under the curve (AUC)/minimum inhibitory concentration ratio during the first 24 - 48 h of treatment is associated with reduced 30-day mortality and greater ...
Mono sulfamethoxazole/trimethoprim and Vancomycin combination antimicrobial zctivity against methicillin-resistant Staphylococcus aureus
Activity of trimethoprim/sulfamethoxazole (SXT) alone or in combination with vancomycin (VAN) was evaluated against methicillin-resistant Staphylococcus aureus (MRSA) from 26 clinical isolates from patients admitted to Hua ...
Vancomycin-resistant enterococcal infection in a Thai university hospital: clinical characteristics, treatment outcomes, and synergistic effect
Purpose: The incidence of infections with vancomycin-resistant enterococci (VRE) is increasing, with associated high mortality rates and limited therapeutic choices. We investigated the clinical characteristics and treatment ...
Identification of blaOXA23 and blaNDM1 from Carbapenem- resistant Acinetobacter baumannii at a Private Hospital in Thailand
OBJECTIVES: This study aimed to detect carbapenemase genes and their clonal relationships among carbapenem-resistant Acinetobacter baumannii (CRAB) clinical isolates.
MATERIAL AND METHODS: Fifteen CRAB isolates were ...