Browsing by Author "Wichai Santimaleeworagun"
Now showing items 1-20 of 29
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Antimicrobial activity profiles and potential antimicrobial regimens against carbapenem-resistant enterobacterales isolated from multi-centers in Western Thailand
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2022)The spread of carbapenem-resistant Enterobacterales (CRE) constitutes a global health burden. Antimicrobial susceptibility and types of carbapenemase differ by geographic region. This study aimed to (1) examine the minimum ... -
Antimicrobials as single and combination therapy for colistin-resistant pseudomonas aeruginosa at a university hospital in Thailand
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2020)Global infections with colistin-resistant Pseudomonas aeruginosa (CoR-PA) are increasing; there are currently very few studies focused on the antimicrobial susceptibility of CoR-PA isolates, and none from Thailand. Here, ... -
Clinical Impact of Vancomycin Treatment in Ampicillin-Susceptible Enterococci Bloodstream Infections
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2022)Enterococci are major causes of bacteremia. Although the mortality rate of ampicillin- susceptible enterococci (ASE) bloodstream infections (BSI) is lower, compared with that of ampicillin-resistant enterococci BSI, the ... -
Clinical outcomes and mortality risk factors among intensive care unit patients with bacteremia at a university hospital
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(Silpakorn University, 2021)This study aimed to determine the prevalence and antimicrobial susceptibility of causative pathogens associated with 30-day mortality among intensive care unit (ICU) patients with bloodstream infections as well as to analyze ... -
Clinical outcomes by treatment type and factors associated with mortality among patients with candidemia at a Thai university hospital
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(The SEAMEO Regional Tropical Medicine and Public Health Network (SEAMEO TROPMED Network), 2020)Candidemia is a major cause of morbidity and mortality among hospitalized patients in Thailand. In this study we aimed to retrospectively investigate the clinical outcomes by treatment regimen and the factors associated ... -
Colistin plus sulbactam or fosfomycin against carbapenem-resistant acinetobacter baumannii: improved efficacy or decreased risk of nephrotoxicity?
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS, 2021)Background Acinetobacter baumannii has been recognized as a cause of nosocomial infection. To date, polymyxins, the last-resort therapeutic agents for carbapenem-resistant A. baumannii (CRAB). Thus, the small number of ... -
A comparison between conventional and stratified antibiograms for antibiotic empirical therapy among the most bacterial pathogens
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(Silpakorn University Research, Innovation and Creativity Administration Office, Sanam Chandra Palace Campus, 2020)Antibiogramsprovideimportant data regarding antimicrobial selection duringempirical therapy and formonitoringyearly trends in antimicrobial resistance in healthcare settings. Antibiograms tailored to hospital location ... -
Does vancomycin resistance increase mortality? clinical outcomes and predictive factors for mortality in patients with enterococcus faecium infections
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2021)The prevalence of enterococcal infection, especially E. faecium, is increasing, and the issue of the impact of vancomycin resistance on clinical outcomes is controversial. This study aimed to investigate the clinical ... -
The First report of a methicillin-resistant staphylococcus aureus isolate harboring type IV SCCmec in Thailand
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2021)Methicillin-resistant Staphylococcus aureus (MRSA) is mostly found in Thailand in the hospital as a nosocomial pathogen. This study aimed to report the genetic characterization of a clinical community-acquired MRSA (CA-MRSA) ... -
Identification of blaOXA23 and blaNDM1 from Carbapenem- resistant Acinetobacter baumannii at a Private Hospital in Thailand
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(Bangkok Dusit Medical Services (BDMS) Foundation, 2019)OBJECTIVES: This study aimed to detect carbapenemase genes and their clonal relationships among carbapenem-resistant Acinetobacter baumannii (CRAB) clinical isolates. MATERIAL AND METHODS: Fifteen CRAB isolates were ... -
Impact of pharmacist-led implementation of a community hospital-based outpatient parenteral antimicrobial therapy on clinical outcomes in Thailand
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2022)Few studies have analyzed community hospital-based parenteral anti-infective therapy (CohPAT). We aimed to assess the clinical impact of a pharmacist-led implementation of a clinical practice guideline (CPG) for CohPAT, ... -
Is Early Monitoring Better? Impact of Early Vancomycin Exposure on Treatment Outcomes and Nephrotoxicity in Patients with Methicillin-Resistant Staphylococcus aureus Infections
Collection: Pride & Awards 2020 - PHARM / ผลงานโดดเด่นปีการศึกษา 2563 - ภศ.Type: Article(Antibiotics, 2020)Optimal early vancomycin target exposure remains controversial. To clarify the therapeutic exposure range, we investigated the association between vancomycin exposure and treatment outcomes or nephrotoxicity in patients ... -
Mono sulfamethoxazole/trimethoprim and Vancomycin combination antimicrobial zctivity against methicillin-resistant Staphylococcus aureus
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(The SEAMEO Regional Tropical Medicine and Public Health Network (SEAMEO TROPMED Network), 2020)Activity of trimethoprim/sulfamethoxazole (SXT) alone or in combination with vancomycin (VAN) was evaluated against methicillin-resistant Staphylococcus aureus (MRSA) from 26 clinical isolates from patients admitted to Hua ... -
Optimal tigecycline dosage regimens in patients infected with carbapenem-resistant Enterobacteriaceae
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(Silpakorn University Research, Innovation and Creativity Administration Office, Sanam Chandra Palace Campus, 2020)We aimed to evaluate the minimum inhibitory concentration (MIC) values of tigecycline for carbapenem-resistant Enterobacteriaceae (CRE) and to identify a potential regimen for achieving target values of the area under the ... -
Optimization of linezolid dosing regimens for treatment of vancomycin-resistant enterococci infection
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS, 2021)Background: Linezolid, an oxazolidinone antibiotic, is recommended for vancomycin-resistant enterococci (VRE). However, 100% free-drug concentration above the minimum inhibitory concentration (fT>MIC) and an area under the ... -
Optimizing doses of ceftolozane/tazobactam as monotherapy or in combination with amikacin to treat carbapenem-resistant pseudomonas aeruginosa
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(MDPI Open Access journal, 2022)Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a hospital-acquired pathogen with a high mortality rate and limited treatment options. We investigated the activity of ceftolozane/tazobactam (C/T) and its synergistic ... -
Optimizing the dosing regimens of tigecycline against vancomycin- resistant enterococci in the treatment of intra-abdominal and skin and soft tissue infections
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS, 2020)Tigecycline was previously considered to have activity against vancomycin-resistant Enterococcus (VRE) isolates, but the optimal dose was not clarified. Thus, this study assessed the in vitro activity of tigecycline against ... -
The plasma concentration profiles and pharmacokinetics of levetiracetam among Thai adult patients undergoing intermittent hemodialysis
Collection: Article - Pharmacy / บทความทางวิชาการ - เภสัชกรรมType: Article(Medical Association of Thailand, 2022)Background: Levetiracetam is a second-generation antiepileptic drug that is primarily eliminated in urine via glomerular filtration and requires dose adjustment in patients with renal insufficiency. However, there are still ... -
The Potential use of ceftazidime-avibactam against carbapenem resistant klebsiella pneumoniae clinical isolates harboring different carbapenemase types in a Thai University Hospital
Collection: Article - Pharmaceutical Care / บทความ - บริบาลทางเภสัชกรรมType: Article(Dove Medical Press : open access to scientific and medical research, 2021)Purpose: MBL and OXA-48 genes in carbapenem-resistant Enterobacterales (CRE) have emerged as a major public health problem worldwide, including Thailand. Due to the lack of susceptibility data and dosing regimens of ... -
Prevalence and Incidence of Iron Deficiency in Patients Undergoing Bariatric Surgery: A Teaching Hospital Experience in Thailand
Collection: Article - Pharmacy / บทความทางวิชาการ - เภสัชกรรมType: Article(Medical Association of Thailand, 2020)Background: Bariatric surgery currently plays an important role in the treatment of obesity. However, iron deficiency and iron deficiency anemia are long-term complications after bariatric surgery. There have been no studies ...