Browsing by Author "Thawatchai Phaechamud"
Now showing items 1-7 of 7
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Combination effects of gambogic acid on imatinib mesylate cytotoxicity in colon cancer cells
Collection: Article - Biomedicine and Health InformaticsType: Article(Trans Tech Publications Ltd., 2020)Imatinib mesylate (IM) is a kinase inhibitor with inhibitory effect on colon cancer cell proliferation. However, some adverse effect of imatinib and drug resistance are challenges for maintenance the therapeutic effect ... -
Development and mechanistic transformation of antimicrobial agent-loaded in-situ forming gel and microparticle using Eudragit RS and rosin as matrix formers for periodontal pocket delivery
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 1/7/2022)This research aimed to prepare and evaluate in situ forming gel (ISG) and in situ forming microparticle (ISM) containing antibiotics for periodontitis treatment employing Eudragit RS (ERS) and rosin (R) as the matrix forming ... -
Injectable antimicrobial agent-loaded in situ forming eudragit L, nitrocellulose and zein-based solvent removal phase-inversion matrices for periodontitis treatment
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 24/11/2023)The in-situ forming matrix (ISM) established through solvent removal phase-inversion, emerges as a promising method for treating periodontitis by administering it to the periodontal pocket. This innovative drug delivery ... -
Mechanistic phase inversion of saturated fatty acid-based in situ forming matrix for pharmaceutical applications
Collection: Theses (Ph.D) - Pharmaceutical Technology / ดุษฎีนิพนธ์ - เทคโนโลยีเภสัชกรรมType: Thesis(Silpakorn University, 18/6/2021)Saturated fatty acids of different chain lengths (C8–C18) were studied as matrix forming agents in this investigation as the localised injectable vancomycin HCl (VCM)-loaded solvent exchange-induced in situ forming matrices ... -
Natural resins-based in situ forming gel for localized antimicrobial and anticancer delivery systems
Collection: Theses (Ph.D) - Pharmaceutical Engineering / ดุษฎีนิพนธ์ - วิศวเภสัชกรรมType: Thesis(Silpakorn University, 25/11/2022)Natural resins such as aloe, benzoin, propolis, rosin and gamboge consist of aqueous insoluble components; therefore, they are possibly applied as matrix forming agents of drug-loaded localized solvent exchange-induced in ... -
Saturated Fatty Acid-Based In Situ Forming Matricesfor Localized Antimicrobial Delivery
Collection: Article - Pharmaceutical Technology / บทความทางวิชาการ - เทคโนโลยีเภสัชกรรมType: Article(Pharmaceutics, 2020-08-25)In recent years, the world has faced the issue of antibiotic resistance. Methicillin-resistantStaphylococcus aureus(MRSA) is a significant problem in various treatments and control of infections.Biocompatible materials ... -
Synergistic anticancer activity of cinnamon bark oil and imatinib mesylate combination on colorectal cancer cell lines
Collection: Article - Biomedicine and Health InformaticsType: Article(Trans Tech Publications Ltd, 2022)Cinnamon bark oil (CO) has anticancer activity in various type of cancer cells and could be used alternatively to support anticancer drugs. For the enhancement of cytotoxic effects, the combination of bioactive compounds ...